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Hyperplasia and hypertrophy of WAT through adipogenesis (e.g., due to excessive energy intake accompanied by low energy expenditure) leads to obesity (Tang and Lane, 2012

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IGF-1 LR3 Mechanism of Action (Research Only) IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 (IGF-1) studied for its interaction with the insulin-like growth factor-1 receptor (IGF-1R), a receptor tyrosine kinase involved in numerous cellular signaling pathways